I don't spray my drawings, but Dennis does. He recommends using the fixative cans which do not have the marble inside.
To send without framing, just pop it between two sheets of cardboard (get a box from your supermarket and cut to size), wrap it and send it.
If you do frame it, it needs to be behind glass, so when shipping ensure you use a good amount of bubble wrap and mark the package as fragile / glass so the delivery dude doesn't just throw it into the truck